Genotyping of clinically relevant human adenoviruses by array-in-well hybridization assay
نویسندگان
چکیده
منابع مشابه
Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant molecular subtypes of glioblastoma.
Glioblastoma, the most aggressive primary brain tumor in humans, exhibits a large degree of molecular heterogeneity. Understanding the molecular pathology of a tumor and its linkage to behavior is an important foundation for developing and evaluating approaches to clinical management. Here we integrate array-comparative genomic hybridization and array-based gene expression profiles to identify ...
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Kinetic hybridization measurements on a microarray are expected to become a valuable tool for genotyping applications. A method has been developed that enables kinetic hybridization measurements of PCR products on a low-density microarray. This is accomplished by pumping a solution containing PCR products up and down through a porous microarray substrate. After every pumping cycle, the fluoresc...
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BACKGROUND Adenoviruses (AdVs) can cause serious disease in immunosuppressed patients, particularly those undergoing allogeneic stem cell transplantation. A method for virus quantification in clinical specimens is essential for monitoring patient adenoviral loads and evaluating new therapeutic approaches. METHODS We developed a PCR-based assay that combines detection and genotyping of human A...
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ژورنال
عنوان ژورنال: Clinical Microbiology and Infection
سال: 2013
ISSN: 1198-743X
DOI: 10.1111/j.1469-0691.2012.03926.x